Immunology - Regulation

Added to site March 2007

• Regulation of Immune Responses by T Cells
• Cutting Edge: CD4⁺CD25⁺ Regulatory T Cells Contribute to Gender Differences in Susceptibility to Experimental Autoimmune Encephalomyelitis
• CD4⁺CD25⁺ T Cells Prevent the Development of Organ-Specific Autoimmune Disease by Inhibiting the Differentiation of Autoreactive Effector T Cells
• FoxP3: A genetic link between immunodeficiency and autoimmune diseases

Added to site November 2005

• Ultraviolet B but not A Radiation Activates Suppressor B Cells in Draining Lymph Nodes
• Regulatory T Cells Induced by Ultraviolet Radiation
• Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair
• Prevention of UV radiation–induced immunosuppression by IL-12 is dependent on DNA repair
• Ultraviolet Radiation-Induced Regulatory T Cells Not Only Inhibit the Induction but Can Suppress the Effector Phase of Contact Hypersensitivity
• Regulation of immunity by self-reactive T cells
• A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3
• Naturally arising Foxp3-expressing CD25⁺ CD4⁺ regulatory T cells in immunological tolerance to self and non-self
• Research highlights
• Natural regulatory T cells in infectious disease
• Mechanisms of suppression by suppressor T cells
• Natural regulatory T cells and self-tolerance
• Essence of harmony
• Cornerstone of peripheral tolerance: naturally occurring CD4⁺ CD25⁺ regulatory T cells
• In Vitro Generation of Interleukin 10–producing Regulatory CD4⁺ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines
• Cutting Edge: Estrogen Drives Expansion of the CD4⁺ CD25⁺ Regulatory T Cell Compartment
• Aging, immunity and cancer
• Pharmacological induction of tolerogenic dendritic cells and regulatory T cells 4
• Autoimmunity on alert: naturally occurring regulatory CD4+CD25+ T cells as part of the evolutionary compromise between a ‘need’ and a ‘risk’
• The inhibition of antigen-presenting activity of dendritic cells resulting from UV irradiation of murine skin is restored by in vitro photorepair of cyclobutane pyrimidine dimers
• Platelet-activating Factor, a Molecular Sensor for Cellular Damage, Activates Systemic Immune Suppression
• Photoimmune suppression and photocacinogenesis
• Mechanisms Underlying the Suppression of Established Immune Responses by Ultraviolet Radiation
• Ultraviolet A Radiation Suppresses an Established Immune Response: Implications for Sunscreen Design
• Mechanisms underlying UV-induced immune suppression: implications for sunscreen design
• Shattuck Lecture — Diversity of the Immune Repertoire and Immunoregulation
• Activation of human CD41 cells with CD3 and CD4⁺ induces a T-regulatory cell 1 phenotype
• Points of control in inflammation
• Induction of regulatory T cells by the immunomodulating cytokines α-melanocyte-stimulating hormone and transforming growth factor-β2
• Plasmid DNA Encoding IFN-γ-Inducible Protein 10 Redirects Antigen-Specific T Cell Polarization and Suppresses Experimental Autoimmune Encephalomyelitis
• B cells regulate autoimmunity by provision of IL-10
• Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
• CD4⁺ CD25⁺ Suppressor T cells: More questions than answers
• Regulatory T cells in autoimmunity
• A T cell receptor transgenic model of severe, spontaneous organ-specific autoimmunity
• Regulation of Interleukin (IL)-18 Receptor α Chain Expression on CD4⁺ T Cells during T Helper (Th)1/Th2 Differentiation: Critical Downregulatory Role of IL-4
• Cutting Edge: Control of CD8⁺ T Cell Activation by CD4⁺CD25⁺ Immunoregulatory Cells